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New treatments for osteoarthritis. Posted by Dr. Badsha, Arthritis clinic in Dubai, UAE

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Unlike Rheumatoid arthritis new treatments for Osteoarthritis have not been available till recently. Very soon a medication called strontium Ranelate or Protelos which has been used for Osteoporosis will receive approval for treatment of Osteoarthritis.

In addition new data surfaced in a study of the popular supplement chondroitin sulfate. Many people with osteoarthritis are taking glucosamine and chondroitin supplements but there has laways been controversy regarding their efficacy. recent data support their use.

Using quantitative magnetic resonance imaging (MRI), researchers have shown in a small clinical trial that chondroitin sulphate (CS) treatment significantly reduces the cartilage volume loss in knee osteoarthritis (OA) starting at six months of treatment, and subchondral bone marrow lesions (BML) at 12 months.1

Published in the Annals of the Rheumatic Diseases, the pilot multicenter randomized, controlled, double-blind trial studied 69 patients with clinical signs of synovitis. Compared with those in the placebo group, patients in the CS group experienced a reduction in cartilage volume loss in the global knee at six months (p=0.030) that persisted at 12 months (p=0.021), a similar reduction at both six and 12 months in the lateral compartment (p=0.015 and p=0.004, respectively), and the tibial plateaus (p=0.002 and p=0.017, respectively). Reductions were also noted at six and 12 months in the lateral and medial tibial plateau, as well as the lateral condyle. The BML data showed no difference between the two groups at six months, but at 12 months there was a trend favoring the CS group (p=0.062 for the global knee, p=0.035 for the lateral compartment, and p=0.044 for the lateral condyle).

 

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This web site is run by an Arthritis Specialist based in Dubai, United Arab Emirates. On this site you will find news about the latest in arthritis, information about research results in the field, tips and information and diet and exercise, and much more.

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