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Gout: An update

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Gout is an often an ignored disease because it can be easily controlled with drug therapy. However, it has reappeared in the last 2 decades. The prevalence of Gout has almost doubled in the United States and this is mainly due to an ageing population, an increase in obesity, hypertension, the popularity of some high protein diets, and the use of thiazide diuretics. Gout is a common problem, affecting about 1% of the population. The male:female ratio is approximately 9:1. Humans are unable to express the enzyme uricase, which can metabolize uric acid, the end product of purine metabolism. As a result there is a ‘normal’ level of uric acid 7 mg/dl (416 umol/l) in men and 6 mg/dl (357 umol/l) in women. A high uric acid level does not necessarily result in gout; other comorbid factors such as hypertension, thiazides, alcohol intake, obesity, and high purine intake increase the risk in an additive manner.

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This web site is run by an Arthritis Specialist based in Dubai, United Arab Emirates. On this site you will find news about the latest in arthritis, information about research results in the field, tips and information and diet and exercise, and much more.

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