Select Category

Black Pepper – a powerful agent to fightArthritis

Go Back

Posted on by

Researchers have found that black pepper can reduce the perception of pain, reduce inflammation, and combat arthritis. These discoveries follow earlier studies showing that black pepper can block complications from diabetes, act as a powerful antioxidant and fight off colon cancer.
Black pepper has been shown to substantially increase the bioavailability of nutrients from food and supplements. This makes including black pepper in your diet, one of the easiest and most economical interventions people can make to boost their overall health!
The study on Piperine
Piperine, the active phenolic compound in black pepper extract, was studied to determine its anti-inflammatory and anti-arthritic effects as well as its ability to reduce the perception of pain. The results showed that
• Piperine inhibited the expression of pro-inflammatory interleukin 6, and MMP13, a gene involved in the promotion of arthritis and metastasis.
• It reduced the production of a pro-inflammatory prostaglandin, even at a very low dose.
When given to arthritic rats, piperine significantly reduced perception of pain and arthritis symptoms. Histological examination showed that piperine significantly reduced the inflammation in their joints (Arthritis Research and Therapy, March 30, 2009).
Piperine increases bioavailability of nutrients from food and supplements
While black pepper improves digestion and frees nutrients for absorption, its piperine compound operates through several other pathways to increase the bioavailability of nutrients from food and supplements. It stimulates amino-acid transporters in the intestinal lining, regulates enzymes that metabolize nutritional substances, and inhibits the removal of substances from cells. Each of these actions allows nutrients to enter and remain within their target cells for longer periods of time than would normally be the case. Through these actions, piperine can turn a marginally effective therapeutic substance into a highly effective one by increasing its intracellular residency time.
Piperine and Curcumin – a potent combination
Curcumin, a compound from the herb turmeric, is known for fighting cancer, pain, inflammation and infection. The action of Curcumin, and thereby its effectiveness, is increased twenty-fold when it is taken with piperine (Planta Medica, May, 1998).

About Arthritis Center

This web site is run by an Arthritis Specialist based in Dubai, United Arab Emirates. On this site you will find news about the latest in arthritis, information about research results in the field, tips and information and diet and exercise, and much more.

More

Archives


Latest Blog

Using your genes to predict if you will respond to Rheumatoid arthritis therapy. (not available in Dubai, UAE at this time)

The ORBIT data “showed that patients who have seropositive rheumatoid arthritis are just as likely to respond to rituximab therapy when compared ...

Read More

Your nose can repair your knee arthritis? Not yet in Dubai!

Doctors might one day be able to harvest cells from patients’ noses to produce cartilage that can be transplanted into damaged knee joints, a sma...

Read More

Green tea to the rescue!

Green tea has always been hailed for its anti-inflammatory properties. But researchers at Washington State University (WSU) in Spokane have now ide...

Read More

This web site is run by an Arthritis Specialist based in Dubai, United Arab Emirates. On this site you will find news about the latest in arthritis, information about research results in the field, tips and information and diet and exercise, and much more.

More

Recent Comments