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Atypical Arthritis Due to Combined Hereditary Hemochromatosis and Active Hepatitis C

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Abstract: A 51 year old white lady presented with asymmetric arthritis and a positive rheumatoid factor. She was initially treated for rheumatoid arthritis. However, she had features such as abnormal liver function tests and osteoarthritis in an unusual location, the metacarpophalangeal (MCP) joint. Further workup revealed that the patient had active hepatitis C and hereditary hemochromatosis. Phlebotomy treatment initiation seemed to be associated with improvement in joint symptoms, but more importantly may have prevented future risk of cirrhosis and hepatocellular cancer. Treatment for the hepatitis C may also be needed. Clinicians should look for underlying systemic illnesses leading to atypical inflammatory arthritis.

Atypical Arthritis Due to Combined Hereditary Hemochromatosis and Active Hepatitis C, was written by Dr. Humeira Badsha, a Consultant Rheumatologist, a member of the Emirates Arthritis Foundation and member of the Emirates Society for Rheumatology. This paper was summited for Journal of Clinical Rheumatology.

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This web site is run by an Arthritis Specialist based in Dubai, United Arab Emirates. On this site you will find news about the latest in arthritis, information about research results in the field, tips and information and diet and exercise, and much more.

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